HIV/AIDS and American Indians/Alaska Natives

American Indian/Alaska Native males had an HIV infection rate that was 29% lower than the total male population in 2023.1
American Indian/Alaska Natives were diagnosed with HIV at a rate that was 39% lower than the total population.1
In 2023, American Indian/Alaska Natives with HIV died at a rate that was 46% lower than the total population.2 The rate for AIDS deaths was 49% lower than the total population.3
- In 2023, American Indian/Alaska Native males with HIV infection died at a rate that was 53% lower than the rate of total male population.
- In 2023, American Indian/Alaska Native females with HIV died at a rate that was 24% lower than the total population of females.

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HIV infection

Diagnoses of HIV Infection among persons ages 13 and older, rate per 100,000 population, 2023
	American Indian/Alaska Native	Total Population	American Indian/Alaska Native/ Total Population Ratio
Male	15.9	22.5	0.71
Female	4.0	5.1	0.78
Total	8.3*	13.7	0.61
*Total rate may include children <13

Source: Centers for Disease Control and Prevention (CDC), 2024. HIV Surveillance Report: Diagnoses, Deaths, and Prevalence of HIV in the United States and 6 Territories and Freely Associated States, 2023, v.35. Tables 3a and 1a.

Diagnoses of HIV infection among children ages 12 and under, rate per 100,000 population, 2023
American Indian/Alaska Native	Total Population	American Indian/Alaska Native / Total Population Ratio
0.3	0.1	3.00

Source: CDC, 2024. HIV Surveillance Report: Diagnoses, Deaths, and Prevalence of HIV in the United States and 6 Territories and Freely Associated States, 2023, v.35. Table 2a.

Diagnoses of HIV infection, Rate, 2023
American Indian/Alaska Native	Total Population	American Indian/Alaska Native / Total Population Ratio
8.3	11.6	0.72

Source: CDC, 2024. HIV Surveillance Report: Diagnoses, Deaths, and Prevalence of HIV in the United States and 6 Territories and Freely Associated States, 2023, v.35. Table 1a.

Persons 13-24 years old living with diagnosed HIV infection, rate per 100,000 population, 2023
American Indian/Alaska Native	Total Population	American Indian/Alaska Native / Total Population Ratio
23.2	53.3	0.44

Source: CDC, 2024. HIV Surveillance Report: Diagnoses, Deaths, and Prevalence of HIV in the United States and 6 Territories and Freely Associated States, 2023, v.35. Table 15a.

AIDS

Prevalence of AIDS among persons age 13 and older, rate per 100,000 population, 2023
	American Indian/Alaska Native	Total Population	American Indian/Alaska Native / Total Population Ratio
Male	104.5	292.5	0.36
Female	33.0	87.4	0.38
Both Sexes	68.0	188.3	0.36

Source: CDC. National Center for HIV, Viral Hepatitis, STD, and Tuberculosis Prevention (NCHHSTP) Atlas Plus. https://gis.cdc.gov/grasp/nchhstpatlas/tables.html

Classifications of persons with Stage 3 (AIDS), by number of cases and percentage, 2023
	Cumulative Cases*	Percent of Total Cases
Total Population	1,366,381	100
American Indian/Alaska Native	3,691	0.002
*Cumulative data are from the beginning of the epidemic through 2023.

Source: CDC, 2025. HIV Surveillance Report: Diagnoses, Deaths, and Prevalence of HIV in the United States and 6 Territories and Freely Associated States, 2023. Slide Set: HIV Infection, Stage 3 (AIDS) 2023. Slide 6. nhss-surveillance-slideset-stage-3-infection-2023.pptx.pptx

Deaths of persons with diagnosed HIV infection, rate per 100,000 population, 2023
	American Indian/Alaska Native	Total Population	American Indian/Alaska Native / Total Population Ratio
Male	4.1	8.7	0.47
Female	1.9	2.5	0.76
Total Population	3.0	5.6	0.54

Source: CDC, 2024. HIV Surveillance Report: Diagnoses, Deaths, and Prevalence of HIV in the United States and 6 Territories and Freely Associated States, 2023, v.35. Tables 12a and 11a.

Deaths of persons ages 13 and older with AIDS, rate per 100,000 population, 2023
	American Indian/Alaska Native	Total Population	American Indian/Alaska Native / Total Population Ratio
Male	3.2	7.7	0.42
Female	1.8	2.2	0.82
Both Sexes	2.5	4.9	0.51

Source: CDC. NCHHSTP Atlas Plus. https://gis.cdc.gov/grasp/nchhstpatlas/tables.html

HIV testing

HIV testing status among persons ages 18 and over, age-adjusted percentage, 2018
	American Indian/Alaska Native	Total Population	American Indian/Alaska Native / Total Population Ratio
Ever tested	46.6	43.7	1.07
Never tested	53.4	56.3	0.95

Source: CDC, 2021. Summary Health Statistics for U.S. Adults: 2018. Table A-20a.

1 Centers for Disease Control and Prevention (CDC), 2024. HIV Surveillance Report: Diagnoses, Deaths, and Prevalence of HIV in the United States and 6 Territories and Freely Associated States, 2023, v.35. Tables 3a and 1a. (Back to top)

2 CDC, 2024. HIV Surveillance Report: Diagnoses, Deaths, and Prevalence of HIV in the United States and 6 Territories and Freely Associated States, 2023, v.35. Tables 12a and 11a. (Back to top)

3 CDC. NCHHSTP Atlas Plus. https://gis.cdc.gov/grasp/nchhstpatlas/tables.html (Back to top)

Date Last Reviewed: September 2025